…requires lifelong pharmacological management. Patients are usually diagnosed between the ages of thirty and fifty, although RA affects all ages. Common co-morbidities include cardiovascular disease, cachexia (muscle wasting), depression and…
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MMF vs AZA for SLE Nephritis
Study Suggests that Genes and Environment Influence the Risk of Developing Rheumatic Disease
…lupus, and scleroderma. Recent immigrants and their second-generation offspring were classified according to their country/region of origin and incidence rates compared to those of native Swedes. The calculated standardized incidence…
Swefot Trial Suggests Adding TNF Inhibitor Better than Triple Therapy in RA Patients who do not Rapidly Respond to Methotrexate
Initial combination therapy has been shown to be superior to step-up combination therapy in groups of RA patients; however, these findings are difficult to reconcile with the observation that many…
Synergistic Benefit Combining Inhibitors of Interleukin-1 and Tumor Necrosis Factor in Rheumatoid Arthritis Model
…comparing the benefits of combination therapy with interleukin-1 receptor antagonist (IL-Ra) and PEGylated soluble tumor necrosis factor receptor type I (PEG sTNFRI) in a rat model of rheumatoid arthritis. Rats…