Knee alignment may be different during walking than when at rest. Prior studies have identified varus thrust, a worsening of bow-leg alignment that occurs only during the weight bearing phase […]
Vitamin D plays an important role in both bone and cartilage homeostasis; however, it is unclear what role vitamin D deficiency and sufficiency play in human osteoarthritis progression. Here, Ding […]
Tai Chi, a popular form of exercise involving stylized and controlled movements, has been advocated as a way to manage pain, maximize function, and improve quality of life for a […]
Inflammatory cytokines, in particular IL-1, are elevated in the synovial fluid of patients with knee osteoarthritis (OA); however, their contribution to OA symptoms and damage are unclear. A small study […]
Glucosamine, with or without chondroitin, is a popular and high selling neutraceutical with claims to improve symptoms associated with painful osteoarthritis (OA). Clinical trials testing purported benefits have yielded mixed results, with manufacturer sponsored trials showing benefits while most unbiased studies have generally not shown benefit over placebo. Previously, in a large clinical trial of glucosamine hydrocholoride with or without chondroitin sulfate, neither agent demonstrated efficacy over placebo in treating pain in individuals with knee OA.