Vitamin D and Sunlight Exposure Are Associated with Reduced Knee Cartilage Loss
Effectiveness of Tai Chi for Musculoskeletal Pain Reviewed
Study Finds No Treatment Benefit of Intra-Articular Anakinra in Knee Osteoarthritis
Chondroitin Sulfate May Act as a Structure Modifying Agent in Knee Osteoarthritis
Glucosamine and/or Chondroitin Not Effective at Reducing Radiographic Progression of Osteoarthritis of the Knee
Glucosamine, with or without chondroitin, is a popular and high selling neutraceutical with claims to improve symptoms associated with painful osteoarthritis (OA). Clinical trials testing purported benefits have yielded mixed results, with manufacturer sponsored trials showing benefits while most unbiased studies have generally not shown benefit over placebo. Previously, in a large clinical trial of glucosamine hydrocholoride with or without chondroitin sulfate, neither agent demonstrated efficacy over placebo in treating pain in individuals with knee OA.