…the most common treatment-related adverse events. In Part B, adverse events were uncommon –with leukopenia being the most common and observed in 7%. Neutrophil counts <1,500 were observed in 5…
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Estrogen Deficiency Induces Bone Loss by Enhancing T Cell Production of TNF alpha news summary by Johns Hopkins Arthritis
…treated with estradiol or placebo. Cultures of bone marrow monocytes (BMM) from OVX athymic mice did not have increased osteoclast formation when compared with sham athymic mice. In the control…
Decorin Deficient Mice Show Resistance to Lyme Disease News Summary from Johns Hopkins Arthritis
…dissemination of Borrelia in joints, heart, bladder and ear tissues. The percent of positive cultures for Borrelia was significantly reduced in Dcn -/- mice compared to Dcn +/- and Dcn…
Transcription of several genes associated with antigen-induced anergy are regulated by rheumatoid arthritis synovial T cells News Summary from Johns Hopkins Arthritis
…compared to an anergic T-cell clone and to T-cells from reactive arthritis (ReA) patients in which no activation defect is known. Transcription of anergy-related transcripts was compared in synovial tissue…
Intraarticular Injection of Infliximab not Effective in Patients with Inflammatory Arthritis
Disease Outcomes of Early Non-Radiographic Spondyloarthropathy Explored
…age of onset did not differ according to whether the patient has AS or non-radiographic SpA. Conclusions Compared to those with AS of comparable disease duration, those with non-radiographic SpA,…