There is a group of diseases called the ‘Spondyloarthropathies’ encompasses several different diseases which include: ankylosing spondylitis, psoriatic arthritis, reactive arthritis, undifferentiated spondyloarthropathy, and inflammatory bowel disease-associated arthritis. Although each of these diseases is unique and has unique characteristics, all of them can involve inflammation of the axial skeleton (spine and sacroiliac joints) which is unique from RA.
Ankylosing Spondylitis Q & A
The FDA approval for both drugs is the same. “Simponi is indicated for the treatment of adult patients with active ankylosing spondylitis””.”” Humira is indicated for reducing signs and symptoms in adult patients with active AS.”” Both medicaations inhibit a cytokine called TNF or tumor necrosis factor. There is no way to predict which will work better or if either will work at all. While TNF inhibitors have helped many people by curbing the progression of AS
One of the characteristics of anklylosing spondilitis is inflammation where tendons attach to the bone. This is a condition called enthesitis. Enthesitis can be painful, especially when it involves tendons in areas frequently used, like the achilles tendon that attaches at the back of the heel.
I don’t recall any studies in which vitamin D intake was specifically studied in anklyosing spondylitis, but there are always benefits to taking Vitamin D. It is a critical molecule that helps build bones, but it has also been discovered to participate in many other critical activities in the body. We rarely get enough vitamin D from the sun because we spend too much time indoors. So, taking a dose by mouth every day is a good idea. It is important, though, to stay within the recommended dosages on the bottle.
Many people complain of more joint pain when it is humid. No one understands exactly why, but folks with arthritis feel that they are barometers, able to sense when a storm is coming !!
Diclofenac is a member of the family of nonsteroidal antiinflammatory drugs (NSAIDs). One of the effects of these drugs is to reduce normal clotting, so the risk during surgery is that bleeding will be hard to stop. So, these drugs should be stopped about 10 days prior to surgery. Usually, they can be restarted 1-2 weeks after surgery. However, you should query your surgeon about these issues also as he/she may have slightly different preferences.