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Arthritis News
Antidrug Antibodies
The development of antidrug antibodies to biologic therapies, notably drugs that consist of monoclonal antibodies (such as adalimumab and infliximab) has been reported in patients with rheumatoid arthritis. However, the clinical significance of these antidrug antibodies in the long-term follow up of RA patients is unknown.
Vaccinations in RA: Stay Healthy!
Vaccinations are a critical component of RA clinical management, and their importance in preventing infection cannot be stressed enough. The majority of patients with RA are on immunosuppressive treatment, and a data driven approach to vaccinations in this high-risk population is essential.
Belimumab: The 1st drug to be FDA approved for the treatment of lupus since 1955
Belimumab is a fully human IgG1λ antibody. It binds to the soluble cytokine, B-lymphocyte stimulator (BLyS) inhibiting its action. BLyS is important for the survival of B lymphocytes, but in patients with systemic lupus erythematosus (SLE) it is overexpressed.
Study Demonstrates Promise for Spleen Tyrosine Kinase (Syk) Inhibitors for the Treatment of Rheumatoid Arthritis
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Lower Dose of Rituximab for RA Treatment Explored
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