…12.4 % 0.028 ACR-N; median (IQR) (-12.5, 28.6) 33.3 (0, 54.4) 0.001 Change in DAS28-CRP; median (IQR) -1.0 (-1.8, -0.2) -1.7 (-2.5, -1.0) 0.002 DAS remission 5.7 % 26.3 %…
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Cardiovascular Risk of Selective COX-2 Inhibitors: Fact or Fiction?
…-then- Parecoxib 20mg IV every 12 hrs for 3 days -then- Valdecoxib 20mg every 12 hrs through day 10 Placebo IV on morning after CABG -then- Placebo IV every 12…
Etanercept and Infliximab Prove Effective in Slowing Joint Damage Caused by Rheumatoid Arthritis
…four groups receiving infliximab plus methotrexate (mean 52%, P<0.001) compared with methotrexate alone (17%). The mean increase from baseline in total radiographic score among all patients receiving a combination of…
FDA Arthritis Drug Advisory Committee Recommends Approval of Febuxostat for Treatment of Hyperuricemia of Gout
Etanercept and Methotrexate Combination Therapy for Rheumatoid Arthritis Treatment
…of disease activity, as compared to 29% of the 30 patients receiving methotrexate plus placebo. By 24 weeks, 39% of the methotrexate plus etanercept met the ACR 50 criteria compared…
Surveillance Study Reports No Increase in Cancer Risk Over First Six years of TNF Inhibitor Use
…individuals with a diagnosis of RA alive in 1998 (when TNF inhibitors were first commercially available). Among these, 6,604 were identified as initiating therapy with a first TNF inhibitor between…