…rheumatoid arthritis (RA). Certolizumab pegol is a novel TNF inhibitor comprised of an antigen-binding domain of a humanized TNF antibody coupled to polyethylene glycol (PEG) to increase half-life, and thus…
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Short-Term Efficacy of a Novel Oral Tyrosine Kinase Inhibitor Demonstrated in Rheumatoid Arthritis
Secukinumab (Cosentyx®)
…rheumatologist. Your doctor will monitor you for any improvements in your disease and for any signs of infections. A Federal Drug Administration approved medication guide can be found at: https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/cosentyx_pmg.pdf…
Pregnancy Outcomes in Infliximab Exposed Women
…included, with follow-up on pregnancy outcomes obtained by telephone or postal contact through early 2003. Pregnancy outcomes of infliximab-exposed women were compared to outcomes of historical controls compiled by the…
What is the Relationship of RA Disease Activity to Radiographic Progression of Joint Damage?
…three years. The second, the Combination Therapy in RA (COBRA) trial cohort, were participants in a 56 week multicenter double-blind trial comparing combination/step-down therapy with monotherapy (see study results). COBRA…
Abatacept Receives FDA Approval for Treatment of RA
…rheumatoid arthritis (RA), there are those who have an inadequate or unsustained response. Abatacept, also known as CTLA4g, blocks a co-stimulatory signal required for T cell activation. In the ATTAIN…