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GI and Cardiovascular Events with Lumiracoxib – Results from the TARGET trial
…comparing lumiracoxib to naproxen (12%) compared to the sub-study comparing lumiracoxib to ibuprofen (8%). In addition, more patients in the lumiracoxib vs. naproxen sub-study were H. pylor positive by serology….
Combination Therapy with Etanercept and Anakinra for Rheumatoid Arthritis
…combination. Editorial Comments: This is the first double-blind, placebo-controlled trial appropriately powered to evaluate the efficacy of this combination regimen. Due to the relatively small numbers of infections, this study…
Complementary and Alternative Medicine for Patients with Rheumatoid Arthritis
…requires lifelong pharmacological management. Patients are usually diagnosed between the ages of thirty and fifty, although RA affects all ages. Common co-morbidities include cardiovascular disease, cachexia (muscle wasting), depression and…
Rheumatoid Arthritis Signs and Symptoms
…syndrome is the most common ocular manifestation of rheumatoid arthritis. Sicca (dry eyes) is a common complaint. Episcleritis occurs occasionally and is manifested by mild pain and intense redness of…
Synergistic Benefit Combining Inhibitors of Interleukin-1 and Tumor Necrosis Factor in Rheumatoid Arthritis Model
…comparing the benefits of combination therapy with interleukin-1 receptor antagonist (IL-Ra) and PEGylated soluble tumor necrosis factor receptor type I (PEG sTNFRI) in a rat model of rheumatoid arthritis. Rats…