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Home / Ask the Expert

Can Methotreate cause nerve pain/neuropathy?

I have been taking methotreate (10 mg a week) for 13 years for psoriatic arthritis. I have developed very servere nerve pain in my feet and ankles. The EMG and nerve conduction studies were negative. A pain specialist mentioned that it was possibly a result of the methotreate. I have not heard that this could be a side effect. Do you have any information on this?

persistant cough

I have had a really bad cough for the last 2 months . I have had 2 rounds of antibiotic but I am also on MTX and plaquenil . Can this have a big effect on why I can not get rid of this ugly cough?

Rheumatoid & Methotrexate

I have recently stopped my methotrexate, and I feel fine. It has been 2 months now, I am wondering exactly what does Methotrexate do for rheumatoid?

Methatrexate and Alcohol

I’m a 33 year old male with psoratic athritis i take 15mg of methatrexate weekly.It really has helped my joints the only thing is that i like the odd beer.Some doctors have told me its ok others say that i should not take any alcohol at all.What would you advise?Thanks for your time.

Psoriatic Arthritis long term prognosis w/o Tx

I am a 49 year old woman, Dx’d with psoriatic arthritis which had gone undiagnoised and untreated for probably 5 years or more, which is in the spine, Just three months ago began seeing Rhumetalogist who put me on methotrexate, but the sed rate of 52 is not moving–he wants to put me on Humira, which I understand seems to show some significance with treating psoriatic arthritis, however, the cost to me with insurance is more than I can afford. I wonder what alternatives there might be if any, and if no real alternatives I would like to know what the long term prognosis is without treatment.

Oral Medications for RA treatment

I have recently been diagnosed with RA after being treated for Polymyalgia for at least a year. My doctor has me on 7.5mg Methotrexate weekly, Plaquenil(GEQ)200mg twice daily,Prednisone 2mg daily and Folic acid 1mg daily. She is now talking about Humira or Enbrel. Can I stay on the oral medications for the long haul(with comparable results) as the new injectables are VERY expensive and I have no insurance?

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Ask The Expert Topics

  • Alternative Therapies
  • Ankylosing Spondylitis
  • Associated With Other Illnesses
  • Bursitis and Tendinitis
  • Corticosteroids
  • Diet and Exercise
  • Disease Modifying Antirheumatic Drugs (DMARDs)
  • Enteropathic Arthritis
  • Fibromyalgia
  • General Arthritis
  • Gout, Pseudogout, Other
  • Infectious Arthritis
  • Myositis
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  • Osteoarthritis
  • Osteonecrosis
  • Osteoporosis
  • Polymyalgia Rheumatica
  • Psoriatic Arthritis
  • Reactive Arthritis
  • Regional Pain: Back and Neck
  • Rehabilitation
  • Rheumatoid Arthritis
  • Surgical Therapy
  • Systemic Lupus Erythematosus (SLE)
  • Systemic Sclerosis
  • Vasculitis
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