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Effects of conventional NSAIDs, selective COX-2 and COX-1 inhibitors on premature labor and closure of the ductus arteriosus in mice
…or COX-2 on days 15-18 of pregnancy. The onset of labor was timed and compared to untreated mice. Histopathology of the DA was examined in pre-term and neonatal mice. [A…
Methotrexate Beneficial in Early Undifferentiated Arthritis
…subjects seropositive for anti-CCP antibodies. Editorial Comment: Much recent debate has focused on whether a “window of opportunity” exists in early RA whereby early aggressive intervention is beneficial. There remains…