…(methotrexate ≤ 25 mg weekly, leflunomide ≤ 20 mg daily, or sulfasalazine ≤ 2000 mg daily), corticosteroids (prednisone ≤ 10 mg daily equivalent), and NSAIDs were permitted. However, co-treatment with…
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Anakinra (Kineret) is Safe and Well Tolerated in RA Patients with Comorbid Conditions from Johns Hopkins Arthritis
…study, Fleischmann et al (Arthritis Rheum 48:927, 2003) evaluated the safety and efficacy of anakinra in patients with and without comorbid conditions and in combination with conventional DMARDs. The preliminary…
Study Suggests that Genes and Environment Influence the Risk of Developing Rheumatic Disease
…risk compared to the native Swedish population were lost in the offspring of immigrants, suggesting that environmental factors also influence the risk of developing rheumatic disease. Editorial Comment This is…
Lost Productive Time and Cost Due to Common Pain Conditions in the US Workforce
…billion dollars are lost due to pain-related conditions that that reduce productivity by compromising performance. Editorial Comments: These results confirm that pain is costly both at the individual and societal…
Johns Hopkins Arthritis News on Celecoxib (Celebrex) Long Term Arthritis Safety Study
Home > Arthritis News > 2000 Celecoxib (Celebrex®) Long-Term Arthritis Safety Study (CLASS) The CLASS study (Silverstein, et al , JAMA 28451247-1255, 2000) is a 6-month, double-blind, randomized controlled trial…
Combination of Methotrexate and Isoniazid Appears Safe for Rheumatoid Arthritis Patients
…that these data do not confirm safety of combining INH with other DMARDs used in RA, with leflunomide being the most likely to result in hepatotoxicity when combined with INH….