…leukopenia or neutropenia. Conclusion: Combination treatment with leflunomide and methotrexate was generally well tolerated and resulted in statistically significant improvement in RA, in comparison to placebo and methotrexate. Therefore, combination…
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Do GPI Antibodies Serve as Biomarkers for Extraarticular Complications of RA?
…These antibodies are uncommon in early or uncomplicated disease. Editorial Comments: Despite small numbers of patients in the groups of patients with extraarticular complications, these results are compelling in drawing…
Demand for Rheumatologists to Outpace Supply
…patient visits than their male counterparts. Conclusions The coming decades will see a substantial shortfall in the number of practicing adult and pediatric rheumatologists in the U.S. Appropriate measures to…
Does Tuberculosis Risk Differ Among TNF Inhibitors?
…TNF inhibitors (e.g. infliximab and adalimumab) compared with decoy receptor TNF inhibitors (e.g. etanercept), there have been few direct comparisons. Here, Dixon et al (Ann Rheum Dis 2010; 69: 522-528)…
Golimumab Shows Promise for the Treatment of Rheumatoid Arthritis
…weeks, then open label infliximab at standard dosing through 44 weeks Golimumab 50 mg every 2 weeks for 20 weeks, then every 4 weeks through week 48 Golimumab 100 mg…
Anakinra (Kineret) is Safe and Well Tolerated in RA Patients with Comorbid Conditions from Johns Hopkins Arthritis
…study, Fleischmann et al (Arthritis Rheum 48:927, 2003) evaluated the safety and efficacy of anakinra in patients with and without comorbid conditions and in combination with conventional DMARDs. The preliminary…