…to assess cardiovascular safety. At the time of the convened analysis, 77% of enrolled subjects had completed the trial, while the remaining 23% had all completed at least 2.8 years…
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Golimumab Shows Promise for the Treatment of Rheumatoid Arthritis
…to 88% of those in the combined golimumab groups. By week 52, 60% of patients in the placebo group remained compared to 79% in the combined golimumab groups (p=0.02). Table….
Etanercept and Methotrexate Combination Therapy for Rheumatoid Arthritis Treatment
…of disease activity, as compared to 29% of the 30 patients receiving methotrexate plus placebo. By 24 weeks, 39% of the methotrexate plus etanercept met the ACR 50 criteria compared…
FDA Arthritis Drug Advisory Committee Recommends Approval of Febuxostat for Treatment of Hyperuricemia of Gout
Does Tuberculosis Risk Differ Among TNF Inhibitors?
…TNF inhibitors (e.g. infliximab and adalimumab) compared with decoy receptor TNF inhibitors (e.g. etanercept), there have been few direct comparisons. Here, Dixon et al (Ann Rheum Dis 2010; 69: 522-528)…
Treatment of Rheumatoid Arthritis with Anakinra (Kineret®) in combination with Methotrexate
…(Arthritis Rheum 46(3):614-624, 2002) examined the safety and efficacy of anakinra in combination with methotrexate compared to methotrexate alone. Methods: In this study 419 subjects were studied who had moderate-to-severe…