…to 88% of those in the combined golimumab groups. By week 52, 60% of patients in the placebo group remained compared to 79% in the combined golimumab groups (p=0.02). Table….
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Cardiovascular Risk of Selective COX-2 Inhibitors: Fact or Fiction?
…to assess cardiovascular safety. At the time of the convened analysis, 77% of enrolled subjects had completed the trial, while the remaining 23% had all completed at least 2.8 years…
FDA Arthritis Drug Advisory Committee Recommends Approval of Febuxostat for Treatment of Hyperuricemia of Gout
Etanercept and Methotrexate Combination Therapy for Rheumatoid Arthritis Treatment
…of disease activity, as compared to 29% of the 30 patients receiving methotrexate plus placebo. By 24 weeks, 39% of the methotrexate plus etanercept met the ACR 50 criteria compared…
Does Tuberculosis Risk Differ Among TNF Inhibitors?
…TNF inhibitors (e.g. infliximab and adalimumab) compared with decoy receptor TNF inhibitors (e.g. etanercept), there have been few direct comparisons. Here, Dixon et al (Ann Rheum Dis 2010; 69: 522-528)…
Etanercept and Infliximab Prove Effective in Slowing Joint Damage Caused by Rheumatoid Arthritis
…four groups receiving infliximab plus methotrexate (mean 52%, P<0.001) compared with methotrexate alone (17%). The mean increase from baseline in total radiographic score among all patients receiving a combination of…