…to 88% of those in the combined golimumab groups. By week 52, 60% of patients in the placebo group remained compared to 79% in the combined golimumab groups (p=0.02). Table….
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Cardiovascular Risk of Selective COX-2 Inhibitors: Fact or Fiction?
…to assess cardiovascular safety. At the time of the convened analysis, 77% of enrolled subjects had completed the trial, while the remaining 23% had all completed at least 2.8 years…
Etanercept and Methotrexate Combination Therapy for Rheumatoid Arthritis Treatment
…of disease activity, as compared to 29% of the 30 patients receiving methotrexate plus placebo. By 24 weeks, 39% of the methotrexate plus etanercept met the ACR 50 criteria compared…
Treatment of Rheumatoid Arthritis with Anakinra (Kineret®) in combination with Methotrexate
…(Arthritis Rheum 46(3):614-624, 2002) examined the safety and efficacy of anakinra in combination with methotrexate compared to methotrexate alone. Methods: In this study 419 subjects were studied who had moderate-to-severe…
Does Tuberculosis Risk Differ Among TNF Inhibitors?
…TNF inhibitors (e.g. infliximab and adalimumab) compared with decoy receptor TNF inhibitors (e.g. etanercept), there have been few direct comparisons. Here, Dixon et al (Ann Rheum Dis 2010; 69: 522-528)…
Does Bone Marrow Edema Predict Progression of Knee Osteoarthritis
…the lateral compartment. In terms of progression of knee OA, of the 39 knees demonstrating progressive joint space narrowing (JSN) of the medial compartment, 27 (69.2%) had medial bone marrow…