Demyelination occuring during Anti-Tumor Necrosis Factor-a Therapy for inflammatory Arthritis The various roles of tumor necrosis factor (TNF) in normal physiologic conditions and disease pathogenesis are not completely understood. However,…
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Does the Serum Concentration of Infliximab (Remicade) Predict Clinical Response?
…the ATTRACT clinical trial, a double-blinded, placebo-controlled trial of infliximab and methotrexate compared to methotrexate alone. Methods: 428 patients with active RA taking stable doses of methotrexate (>12.5 mg), NSAIDS,…
Inhaled Glucocorticoids Leads to Dose-Related Bone Loss in Premenopausal Women News Summary from Johns Hopkins Arthritis
Inhaled Glucocorticoids Leads to Dose Related Bone Loss in Premenopausal Women Inhaled glucocorticoids are commonly prescribed for long-term asthma treatment. Although it has been established that oral glucocorticoid therapy accelerates…
Ankylosing Spondylitis
…the United States is approximately 0.2-0.5%. Based on data from multiple countries, the age- and sex-adjusted incidence of AS is 0.4-14 per 100,000 person-years. Prevalence of AS in the population increases to approximately…
Rheumatology Clinics
…and the Johns Hopkins Hospital Outpatient Center. At these facilities, over 100 new patients and 400 return patients are seen weekly who have complex rheumatic diseases & common musculoskeletal problems….
Brain Centers Responsible for Emotion and Fear Process OA Pain
Pain perception in osteoarthritis (OA) is complex, with the intensity of pain reported in affected individuals often with little correlation to structural damage. Few studies have explored the neural networks…