…the risk of progression to severe activity difficulty. The authors conclude that widespread pain is frequent among older disabled women and also predict progression to severe disability. Editorial Comment: This…
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Efficacy of Leflunomide (Arava) in Treatment of Rheumatoid Arthritis
…358 patients were randomly assigned to one of three treatments for 6 months: leflunomide (100 mg daily on days 1-3, then 20 mg daily); sulfasalazine (0.5g qd, titrated up to…
Predictors and Frequency of Infection in RA Patients
…a companion retrospective cohort study. Methods: Doran et al conducted a retrospective longitudinal population-based cohort study comparing rates of infection in 609 RA patients to 609 randomly selected age and…
Rituximab Non-responders do not Benefit from Repeated Treatments
Quadriceps Strengthening Does Not Protect Malaligned and Lax Knees from Subsequent Progression of Knee Osteoarthritis (OA) News from Johns Hopkins Arthritis
…measured at baseline. Semi-flexed radiographs of both knees were obtained at baseline and 18 months to measure OA progression in the medial and lateral compartments, as well as the patello-femoral…
Incidence of Cardiovascular Events in Patients Treated with TNF Inhibitors
…inhibitors demonstrated incident CVD morbidity in a range compatible with the background incidence of CVD morbidity in the local community. Editorial Comment: This report is the first population-based investigation to…