…study, Fleischmann et al (Arthritis Rheum 48:927, 2003) evaluated the safety and efficacy of anakinra in patients with and without comorbid conditions and in combination with conventional DMARDs. The preliminary…
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Apremilast (Otezla) approved by FDA
Lost Productive Time and Cost Due to Common Pain Conditions in the US Workforce
…billion dollars are lost due to pain-related conditions that that reduce productivity by compromising performance. Editorial Comments: These results confirm that pain is costly both at the individual and societal…
Combination of Methotrexate and Isoniazid Appears Safe for Rheumatoid Arthritis Patients
…that these data do not confirm safety of combining INH with other DMARDs used in RA, with leflunomide being the most likely to result in hepatotoxicity when combined with INH….
Golimumab Shows Promise for the Treatment of Rheumatoid Arthritis
…to 88% of those in the combined golimumab groups. By week 52, 60% of patients in the placebo group remained compared to 79% in the combined golimumab groups (p=0.02). Table….
Cardiovascular Risk of Selective COX-2 Inhibitors: Fact or Fiction?
…to assess cardiovascular safety. At the time of the convened analysis, 77% of enrolled subjects had completed the trial, while the remaining 23% had all completed at least 2.8 years…