…syndrome is the most common ocular manifestation of rheumatoid arthritis. Sicca (dry eyes) is a common complaint. Episcleritis occurs occasionally and is manifested by mild pain and intense redness of…
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Combination Therapy with Etanercept and Anakinra for Rheumatoid Arthritis
…of three groups: etanercept 25 mg twice a week + anakinra placebo QD + background methotrexate etanercept 25 mg QW + anakinra 100 mg QD + background methotrexate etanercept 25…
Do Race, Ethnicity, and Geographic Location Influence the Rate of Knee Arthroplasty?
…variability. Using a comprehensive, nationwide cohort, Skinner et al (NEJM 349(14):1350, 2003) examine the influence of race, ethnicity, and geographic location on rates of knee arthroplasty. Methods: The U.S. Medicare…
Synergistic Benefit Combining Inhibitors of Interleukin-1 and Tumor Necrosis Factor in Rheumatoid Arthritis Model
…combination. Paw and joint swelling, paw weights, and histology were monitored. In rats with CIA, combination therapy with 100 mg/kg IL-1Ra and all doses of PEG sTNFRI resulted in additive…
GI and Cardiovascular Events with Lumiracoxib – Results from the TARGET trial
…comparing lumiracoxib to naproxen (12%) compared to the sub-study comparing lumiracoxib to ibuprofen (8%). In addition, more patients in the lumiracoxib vs. naproxen sub-study were H. pylor positive by serology….
Complementary and Alternative Medicine for Patients with Rheumatoid Arthritis
…requires lifelong pharmacological management. Patients are usually diagnosed between the ages of thirty and fifty, although RA affects all ages. Common co-morbidities include cardiovascular disease, cachexia (muscle wasting), depression and…