Demyelination occuring during Anti-Tumor Necrosis Factor-a Therapy for inflammatory Arthritis The various roles of tumor necrosis factor (TNF) in normal physiologic conditions and disease pathogenesis are not completely understood. However,…
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Does the Serum Concentration of Infliximab (Remicade) Predict Clinical Response?
…the ATTRACT clinical trial, a double-blinded, placebo-controlled trial of infliximab and methotrexate compared to methotrexate alone. Methods: 428 patients with active RA taking stable doses of methotrexate (>12.5 mg), NSAIDS,…
Do Cyclooxygenase Inhibitors Alter the Antiplatelet Effects of Aspirin?
…other NSAIDs, it was of interest to determine whether such a regimen would negate the beneficial effects of aspirin through competitive inhibition. That is, the NSAID might block aspirin from…
Inhaled Glucocorticoids Leads to Dose-Related Bone Loss in Premenopausal Women News Summary from Johns Hopkins Arthritis
Inhaled Glucocorticoids Leads to Dose Related Bone Loss in Premenopausal Women Inhaled glucocorticoids are commonly prescribed for long-term asthma treatment. Although it has been established that oral glucocorticoid therapy accelerates…
Ankylosing Spondylitis
…the United States is approximately 0.2-0.5%. Based on data from multiple countries, the age- and sex-adjusted incidence of AS is 0.4-14 per 100,000 person-years. Prevalence of AS in the population increases to approximately…
Nutrition & Rheumatoid Arthritis
…diets, exceeds well over one million dollars annually. In 1989, Arthritis Care(ref 1) noted that greater than 50% of the Arthritis Care members who were surveyed, had invested in “unorthodox…