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Home / Ask the Expert / zero negative rheumatoid arthritis

zero negative rheumatoid arthritis

April 26, 2007 By Arthritis Center

Question

what is this compared to positive rehumatoid arthritis and can the above mentioned turn into positive arthritis. what is my future prognosis. I am a soon to be 47 yr old female.

Answer

Rheumatoid factor is a commonly ordered blood test to help diagnose rheumatoid arthritis. About 70-90% of people with adult rheumatoid arthritis are positive for rheumatoid factor and about 20% of people remain negative for rheumatoid factor even though they have been diagnosed with rheumatoid arthritis. Therefore, a positive test for rheumatoid factor is by no means necessary to indicate disease.

The result does not correlate with the activity of disease, but patients with a high amount rheumatoid factor are more likely to have erosive joint disease, extra-articular manifestations, and greater functional disability. In contrast, generally, rheumatoid factor negative patients exhibit a milder disease course.

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