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Home / Ask the Expert / Re: rheumatoid arthriris

Re: rheumatoid arthriris

April 26, 2007 By Arthritis Center

Question

What’s the difference between Zero Positive R.A and Zero Negative R.A. What repercussions does these two have over joints?

Answer

The terms are “seropositive” and “seronegative” rheumatoid arthritis. Seropositive means that the rheumatoid factor blood test is positive (present), and seronegative means that it is negative. About 15% of RA patients are seronegative. In general, but not always, seropositive patients have less severe disease– fewer deformities, less joint swelling, less joint destruction and less disability.

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