I take a relatively low dosage of methotrexate once a week. I feel weak, tired and slightly sick for a day and a half after each dose. I also take hydroxychoroquine. I stopped the methotrexate for a couple of weeks and felt great but towards the end of the two weeks my RA symptoms returned. My blood work is normal. I don’t want to get 5 days of relief for two days of feeling sick every week. Are there other DMARDS that I should try?
Talk to your rheumatologist and look at our RA treatment section on this website. Arava (leflunomide) or one of the TNF inhibitors (Humira, Enbrel, Remicade) might be appropriate.