I am a 50 year old female facing knee replacement on one knee and a partial replacement on the other. I suffer from arthritis and take Bextra 20 mg daily. I have been on HRT since age 27 (recently stopped) treated with Estratest. I suffer chronic pain (4 years now) from cervical disk disease treated with Percocet 10/650 4 to 5 tablets daily. To complicate all of these matters I consume 8 or more cups of coffee daily. I am wondering if any of the drugs/caffeine could be causing the problems with my knees or increasing my arthritis pain. It is hard for me to believe I must have knee replacement at 50.
None of the problems you mentioned have been directly linked to osteoarthritis of the knees. But I would imagine that your overall musculoskeletal health is poor adding to diffculties of OA.