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Home / Ask the Expert / Elevated CPK from Excercise

Elevated CPK from Excercise

September 10, 2007 By Arthritis Center

Question

medical history, the client had cholesterol and no trygliceride, and from his family diabetic history he is predisposed to have diabetes, but not taking any medications . We started the first two weeks with a cardio exercise (not Exceeding 75% of the heart rate reserve), with body weight floor exercises. After two weeks, I did the 1RM testing on the weight training machines. The subject was feeling great training 6 days a week. After one month, he was hyper and and sleeping only 3 hours a day. I asked him to check with the physician. he did a blood test and his cpk level was high (around 5600). Normally the first question was if he uses cocaine, but the answer was no. His phsyician told him to stop exercising for 10 days, and asked for a calium/potassium test. What do you think the problem is?  Would it be rhabdomyolisis?I am a personal trainer. I have a client who started to train with me a month ago.

Answer

There are some interesting inhereted enzyme defects that can result in elevated CPK.  The most likely in this situation is carnitine palmitoyl transferase deficiency, in which CPK levels are normal or high normal into adulthood, but may become very elevated with physical activity.  Additional work-up for you client is warranted and can be directed by his primary provider.  It would be advisable for him to discontinue intense physical activity until the source of the problem is determined.

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