Dear Sir/Madam I am 64 years old. Seven years ago, I was diagnosed with RA and several years later, with Fibromyalga. For the past six years, I have been taking methotrexate, enbrel, plaquinil and codeine for pain relief. I recently consulted my family doctor about unexplained weight gain, unusual because my appetite is poor. He is having numerous tests done which hopefully will explain the edema which he thinks I have. I am undergoing all the tests,but can the drugs I am taking possibly be a cause of the edema? Thanks for your time.
In general, the drugs that you list do not cause edema. The arthritis drugs that can cause edema are the non-steroidal antiinflammatory drugs (NSAIDs) like ibuprofen, naproxen, celecoxib, etc.