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Home / Ask the Expert / High rheumatoid factor – what does it mean?

High rheumatoid factor – what does it mean?

January 24, 2010 By Arthritis Center

Question

My RA factor is 412 butand my Sed is normal. what could cause such a high RA factor? It was checked 3 times just to make sure it wasnt a mistake. Thank You

Answer

HI Victoria,

An interesting question.  Why was the RA factor drawn in the first place?  I assume you were having some joint pain.  A positive rheumatoid factor can be found in other conditions besides RA, like chronic infections.  However, a very high level like this is a clue that RA MIGHT (not definite but MIGHT) develop in the future, even if it is not there now.   So, someone with a very positive RF should be seen by a rheumatologist and followed periodically.  IF there is already joint pain present, then a visit to a rheumatologist is a must !!

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