• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer

Johns Hopkins Arthritis Center

Show Search
Hide Search
  • Disease Information
    • Rheumatoid Arthritis
    • Psoriatic Arthritis
    • Ankylosing Spondylitis
    • Osteoarthritis
    • Gout
    • Osteoporosis
  • Patient Corner
    • Drug Information Sheets
    • Managing Your Arthritis
    • RheumTV – Patient Education Video Library
  • Our Research
    • Patient-Centered Outcomes Research
    • Current Research Studies
    • The Camille Julia Morgan Arthritis Research and Education Fund
  • About Us
    • Appointment Information
    • Contact Us
    • Our Faculty
    • Our Staff
    • Rheumatology Specialty Centers
    • News & Updates
  • Donate
Home / Ask the Expert / Follow-up on 21 days of antibiotic for Lyme Disease

Follow-up on 21 days of antibiotic for Lyme Disease

April 12, 2007 By Arthritis Center

Question

One month ago I tested positive for Lyme Disease, after going to my internist with a large rash on my shoulder. (The rash turned into a classic bulls-eye over 5 cm wide.) My doctor prescribed 2 weeks of doxycycline. But my friends and I had heard the treatment was longer. So after I searched the CDC and Johns Hopkins website for the standard treatment, I asked for 2 more weeks of antibiotic. My doctor refused and only would prescribe 1 more week for a total of 21 days. (Her reasoning was the extended antibiotic could be harmful to my intestinal flora since I had also taken 10 days of eurythromycin sp? to treat a rapid skin infection that had developed in the rash cellulitis?) It has been over 1 week since my 3 week antibiotic was finished and I am starting to feel very fatigued, somewhat achy and flu like. I am concerned that I didn’t stay on antibiotics long enough. Is there a standard treatment/testing procedure once a patient has finished the initial course of antibiotics? E.g., when should I get re-tested?

Answer

There is no accepted test to verify that the treatment has been successful. The decision to treat with an additional course of antibiotics is based on clinical signs and symptoms.

Arthritis Center

Founded in 1998, the Arthritis Center at Johns Hopkins is dedicated to providing quality education to patients and healthcare providers alike.

Primary Sidebar

Ask The Expert Topics

  • Alternative Therapies
  • Ankylosing Spondylitis
  • Associated With Other Illnesses
  • Bursitis and Tendinitis
  • Corticosteroids
  • Diet and Exercise
  • Disease Modifying Antirheumatic Drugs (DMARDs)
  • Enteropathic Arthritis
  • Fibromyalgia
  • General Arthritis
  • Gout, Pseudogout, Other
  • Infectious Arthritis
  • Myositis
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  • Osteoarthritis
  • Osteonecrosis
  • Osteoporosis
  • Polymyalgia Rheumatica
  • Psoriatic Arthritis
  • Reactive Arthritis
  • Regional Pain: Back and Neck
  • Rehabilitation
  • Rheumatoid Arthritis
  • Surgical Therapy
  • Systemic Lupus Erythematosus (SLE)
  • Systemic Sclerosis
  • Vasculitis
RheumTV Logo

Rheum.TV is an informational platform created to educate patients living with a rheumatic disease. With over 100 disease education videos produced by the team at Johns Hopkins Rheumatology.

Visit Rheum.TV

Footer

Johns Hopkins Rheumatology

  • Johns Hopkins Rheumatology
  • Johns Hopkins Lupus Center
  • Johns Hopkins Lyme Disease Research Center
  • Johns Hopkins Myositis Center
  • Johns Hopkins Scleroderma Center
  • Johns Hopkins Sjögren’s Syndrome Center
  • Johns Hopkins Vasculitis Center

Connect With Us

  • Facebook
  • Twitter
  • YouTube

Johns Hopkins Medicine

© 2025 Johns Hopkins Arthritis Center
Patient Privacy