What is Seropositive RA?


I have RA for 10 yrs and have just been diagnosed with having seropositive RA what is this and what does it mean.


Seropositive simply means that your rheumatoid factor blood test is positive. Some also count the anti-CCP positive test as seropositive.  In general, patients develop positive rheumatoid factor within one year of developing symptoms.  Overall, patients who are seropositive have a more severe disease course with more joint deformities, x-ray damage, disability and inflammation outside of the joints.  However, there are many exceptions to these rules.

Alan Matsumoto, M.D.

About Alan Matsumoto, M.D.

Part-time Faculty, Division of Rheumatology
Johns Hopkins University