What is Ryder’s Syndrome?

Question

What is Ryder’s Syndrome, and where can I find detailed information on its symptoms, treatment, genetic pre-disposition, etc.?

Answer

Its not the truck rental company but rather Reiter’s syndrome named after Dr. Hans Reiter. The syndrome is the combination of inflammatory arthritis (mainly one or two large lower extremity joints- knees or ankles), conjunctivitis and urethritis (inflammation of the tube that passes urine). It often occurs after a gastrointestinal or genitourinary infection. it is more common in men and in those men carrying the HLAB27 genetic marker. Treatment is with NSAIDs and prognosis is generally good with the attacks becoming less frequent over time.

Alan Matsumoto, M.D.

About Alan Matsumoto, M.D.

Part-time Faculty, Division of Rheumatology
Johns Hopkins University