I have also read Dr. Wigley’s articles on this. To my knowledge, the level of increased risk is unclear. I also do not know if any specific therapy that has been shown to decrease the risk in patients with Raynauds. It makes sense however to pay attention blood preswsure control, cholesterol control and possibly use low dose aspirin. You might also talk to your doctor about testing for homocysteine levels.
About Alan Matsumoto, M.D.
Part-time Faculty, Division of Rheumatology
Johns Hopkins University