Lyme disease treatment concerns? Question My cousin is battling Lyme disease and sought help through the Mayo Clinic in the Midwest…discovering that Mayo does NOT accept Lyme disease as a real illness….why is this as Hopkins does address this disease? Answer August 1, 2007 By Alan Matsumoto, M.D. You must be mistaken. Mayo may not have a program for Lyme patients because the infection is much less common in their area, than on the East Coast.