In many cases, the trigger for vasculitis remains unknown. In some types of vasculitis such as polyarteritis nodosa (PAN), there is a strong link with hepatitis B and C virus raising speculation that the virus or the response to the virus triggers the inflammation. The course of vasculitis is unpredictable but in many cases the disease quiets or “burns out” over roughly a 2-3 year period of time– the reason for this is also unknown.
About Alan Matsumoto, M.D.
Part-time Faculty, Division of Rheumatology
Johns Hopkins University