High ANA and miscarriage

Question

I have been having bloodwork at intervals for last 18 months, latest ANA positive 1:2560, screamingly high result as quoted by consultant haematologist however with negative DNA result. have been told Cannot be diagnosed as SLE but some type of auto immune disorder-generally feel unwell most of the time with pain throughout body, exhaustion, miscarried Feb 08-feel frustrated as no nearer to finding underlying cause or treatment-any advice much appreciated. regards andrea

Answer

HI Andrea,

Someone with a very high titer ANA and a miscarriage should be evaluated by a rheumatologist.  Even though there may not be enough symptoms to reach a dianosis of lupus, there is something brewing that needs to be evaluated and watched.  Miscarriages are common in lupus and in something else called anti-phospholipid antibody syndrome (also called anti-cardiolipin antibody syndrome).

Joan Bathon, M.D.

About Joan Bathon, M.D.

Dr. Bathon was a Co-Deputy Director of the Division of Rheumatology at Hopkins Bayview. She was also the founder and director of the Hopkins Arthritis Center.