CPK is an enzyme that is found within muscle cells. When the muscle cells are damaged for any reason, the CPK is released into the blood and the test is elevated. Normal CPK levels are in the range of 250 or less. There are many causes of CPK elevation and muscle damage. Drugs (prescription and illicit), trauma (temporary elevation of CPK), inflammation (myositis), alcohol, genetic porblems with the muscle, viral infections can all cause CPK elevation. I would suggest an evaluation by a rheumatologist.
About Alan Matsumoto, M.D.
Part-time Faculty, Division of Rheumatology
Johns Hopkins University