MTX dose not have a direct toxic effect on the lungs. A very small group of patients can experience an allergic type reaction in the lung to MTX, but this is fairly rare and generally clears when MTX is stopped.
Effects of methotrexate in the lungs.
July 16, 2007 By
Question
What are the effects of methotrexate in the lungs, short and long term. (for a WG patient)

