Allergic reactions and serious infections from DMARDS

Ive been on 15mg of MTX for 2 years but need more help. My Rhematologist has suggested anti TNF. Is it true that there are more side effects in terms of allergic reactions and serious infections with Humira Than with Enbrel? Also I asked about the TB test and my RA team don’t do it!! I live in the UK.

Concerned with increasing Methotrexate

I have arthritis and am being treating with methotraxate and enbrel which was working superbly until recently when I started having strange sensations in my head and experienced extreme fatigue which might relate to an increase to 15 mg for the methotraxate. I am concerned as these side effects somewhat negate the excellent results achieved so far. Could an addition of folic acid help. Many Thanks for your advise. Kind Regards Simon

Efficacy of Sulfasalazine?

Hi, I’m 19 and I was diagnosed with RA in November last year. Before I was diagnosed I was put on 20mg prednisolone, etoricoxib 90mg and co-codemol. Once diagnosed I was put on methotrexate and folic acid, with the aim of incresing the MTX up to 20mg and decreasing the pred. I was taken off MTX in January due to a chronic cough and little response, and put on sulfasalazine 2g. Since then I have been trying to decrease the pred. I am now on 9mg daily. Every time I decrease the dose of pred I have a flare which lasts for about a week. Does the fact that I am flaring as I decrease the pred mean that the sulfasalazine is not sufficiently controlling the disease? I have now been on sulfasalazine for four and half months.