Total knee replacement (TKR) is an effective, yet underutilized, treatment for severe knee osteoarthritis (OA). In particular, eligible minority patients tend to undergo TKR less often than white patients. The origins of these racial/ethnic disparities are incompletely understood, but may include both care-based (e.g. physician bias for recommending TKR) and patient-based (e.g. decisions not to undergo TKR if recommended) factors.
Safety and Efficacy of Leflunomide in Patients with Juvenile Rheumatoid Arthritis (JRA)
Active polyarticular juvenile rheumatoid arthritis (JRA) can result in significant joint destruction, deformity, and lifelong loss of physical function. NSAIDs, generally effective in controlling the symptoms of the pauciarticular form of JRA, are often not adequately effective in polyarticular JRA. Although many JRA patients are treated with the same DMARDs used to treat adult-onset RA (i.e. methotrexate, sulfasalazine, etc), few controlled clinical trials of DMARDs have been conducted in JRA patients.
Infliximab Now Approved for Use in Ankylosing Spondylitis; Centocor Updates Warning Label
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Hurricane Katrina and Arthritis Patients
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Febuxostat Submitted for FDA Approval in Chronic Gout
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Comparison of Febuxostat and Allopurinol on Serum Urate Levels
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