The Food and Drug Administration (FDA) has now approved abatacept (Orencia®) for the treatment of rheumatoid arthritis (RA). It is the first approved agent to demonstrate efficacy and safety in patients with an inadequate response to TNF antagonists, as well as those with an inadequate response to MTX.
Improved Cardio-Respiratory Fitness with Prescribed Exercise
Regular physical activity improves general health but the frequency and intensity of physical activity required to produce benefits is not clear. To address this issue, Duncan and associates (Archives of Internal Medicine, 2005; 165: 2362-2369) conducted a randomized controlled clinical trial to evaluate the effects of different prescriptions of exercise intensity and frequency on cardiovascular disease risk factors.
Consequences of Physical Activity on Life Expectancy
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Medicare Part D – Medicare’s New Prescription Drug Program
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Intra-articular Transfer of Genes has Therapeutic Potential in Inflammatory Arthritis
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Is There an Association Between Knee Height and the Prevalence of Knee Pain?
Mechanical forces exerted on the knee contribute to the development of knee osteoarthritis (OA). Among these, the additional torque about the knee associated with increasing leg length may predispose people of taller stature to knee OA. However, this association has received little prior investigation. In contrast to body height, which may decrease with age, knee height is relatively constant, making knee height a more appropriate surrogate for stature in the elderly.
