Recently approved by the FDA for use in rheumatoid arthritis, Leflunomide (AravaTM) made by Hoechst Marion Roussel was officially launched in October. The first new approved disease-modifying agent (second-line) since the approval of methotrexate in the late 1980’s, leflunomide provides a new option for patients with rheumatoid arthritis particularly those who have failed or were intolerant to traditional disease-modifying agents. New Phase II and III clinical trial data were presented at the 1998 American College of Rheumatology Meeting.
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