Knee pain from osteoarthritis (OA) tends to be poorly correlated to degree of cartilage loss. Other factors related to knee OA, including bone marrow edema and synovitis, may be more proximal determinants of pain in knee OA. Synovitis is usually quite limited in knee OA and difficult to quantify on physical exam. Magnetic resonance (MR) imaging is a more sensitive technique for assessing synovitis in knee OA.
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