Anakinra (Kineret®)

What is Anakinra (Kineret®)?

Anakinra is injected under the skin to reduce signs and symptoms of rheumatoid arthritis, such as joint swelling, pain, tiredness, and duration of morning stiffness. Anakinra is commonly known as Kineret® and is an IL-1 inhibitor.

How do I take it?

Anakinra is injected under the skin (similar to insulin injections) every two week. The injections are 100-mg. each. You will be instructed on how to give yourself injections. You should make sure you have a complete understanding of how to prepare and give the injection, and how to dispose of the empty syringes before beginning this treatment. Do not take more or less medicine than ordered. THIS MEDICATION MUST BE REFRIGERATED. Do not freeze this medicine.

What else should I know?

Inform your doctor if you have a history of recurring infections. Your physician will do periodic blood tests to check your blood counts. Let your doctor know if you have a latex allergy, (syringes and gloves contain latex products). You will be monitored periodically to check the effectiveness of this treatment. Your doctor may want to stop Kineret if you develop a serious infection.

Notify your doctor if you have any signs or symptoms of a serious infection, such as high fever, pneumonia, sinus infection or kidney infection.

What about other medications?

When you are taking Anakinra, it is very important that your doctors know if you are taking any other medicine. This includes prescription and non-prescription medicines as well as birth control pills, vitamins, and herbal supplements.

Anakinra can be taken with other medications – NSAIDS (Celebrex®, Vioxx®, ibuprofen, naproxen), prednisone, methotrexate, and plaquenil. It cannot be taken with TNF inhibitors, such as Enbrel®, Remicade®, and Humira™.

Updated: April 25, 2012

Victoria Ruffing, RN

About Victoria Ruffing, RN

Ms. Ruffing has been a member of the Arthritis Center since 2000, currently serving as the Nurse Manager. She is a critical member of our patient care team.