Arthritis Center Research Studies

Enrolling

CORRONA Psoriatic and Spondyloarthritis Registry Research Study

Posted 3/11/2014

Purpose of Study: This research is being done to gather information about patients with certain rheumatic diseases. The CORRONA Organization is building a comprehensive database of information concerning rheumatology patients as part of its mission to facilitate research.

Recruiting Patients:

  • Diagnosed with Psoriatic or Spondyloarthritis
  • Patients of the Johns Hopkins Arthritis Center
Coordinator/Contact: Michelle Jones
410-550-9674
Email: mrkjones@jhmi.edu
Principal Investigator: Clifton O. Bingham, M.D.
IRB#: NA_00092661

The PRESS ERA: The protein and resistance exercise supplementation study for elderly with rheumatoid arthritis

Posted 2/10/2014

Purpose of Study: This study is being done to look at the effects of resistance exercise and protein supplementation on body fat, muscle mass, muscle strength, mood, and quality of life in people with Rheumatoid Arthritis.

Recruiting Patients:

  • Diagnosed with Rheumatoid Arthritis
  • Men and women aged 60-95 years old
Coordinator/Contact: Marilyn C. Towns
410-550-0579
Email: mctowns@jhmi.edu
Principal Investigator: Rebecca Manno, M.D.
IRB#: NA_00088317

Mesoblast MSB-RA001, A Double-blind, Randomized, Placebo-controlled, Dose-escalation, Multi-center Study of a Single Intravenous Infusion of Allogeneic Mesenchymal Precursor Cells (MPCs) in Patients with Rheumatoid Arthritis and Incomplete Response to at Least One TNFα Inhibitor.

Posted 2/10/2014

Purpose of Study: This study is being done to understand if Mesenchymal Precursor Cells can control the signs and symptoms of RA in patients who have failed at least one TNF-alpha inhibitor.

Recruiting Patients:

  • Active rheumatoid arthritis
  • Taking methotrexate for at least six months
  • History of taking at least one TNF-alpha inhibitor that has failed to adequately control RA
  • Men and women age 18 – 80 years old
Coordinator/Contact: Marilyn C. Towns
410-550-0579
Email: mctowns@jhmi.edu
Principal Investigator: Clifton O. Bingham, M.D.
IRB#: NA_00083896

Resistance Exercise in Rheumatic Disease

Posted 8/16/2013

Purpose of Study: This study is being done to look at the effects of resistance exercise on body fat, muscle strength, mood, and quality of life in people with Rheumatoid Arthritis and Vasculitis after 16 weeks.

Recruiting Patients:

  • Diagnosed with Rheumatoid Arthritis or Vasculitis
  • Men and women aged 45-85 years old
Coordinator/Contact: Marilyn C. Towns
410-550-0579
Email: mctowns@jhmi.edu
Principal Investigator: Rebecca Manno, M.D.
IRB#: NA_00069415

Prospective Validation of Soluble Biomarkers as Predictors of Structural Damage in Rheumatoid Arthritis (RA BIODAM)

Updated 7/13/2012

Purpose of Study: The purpose of this research study is to measure how active a patient’s rheumatoid arthritis (RA) is, how to predict what medications will work best, and to predict which patients will develop joint damage over time by identifying biomarkers in the blood and urine.

Coordinator/Contact: Marilyn C. Towns
Principal Investigator: Clifton O. Bingham, M.D.
IRB#: NA_00041600

CORRONA Data Collection Program

Updated 8/23/2012

Purpose of Study: This research is being done to gather information about patients with certain rheumatic diseases. The CORRONA Organization is building a comprehensive database of information concerning rheumatology patients as part of its mission to facilitate research.esearch is being done to gather information about patients with certain rheumatic diseases. The CORRONA Organization is building a comprehensive database of information concerning rheumatology patients as part of its mission to facilitate research.

Recruiting Patients:

  • Diagnosed with Rheumatoid Arthritis or Psoriatic Arthritis
  • Patients of the Johns Hopkins Arthritis Center
Coordinator/Contact: Michelle Jones
410-5509674
Email: mrkjones@jhmi.edu 
Principal Investigator: Clifton O. Bingham, M.D.
IRB#: NA_00027956

Pilot Study of Implementing the Patient Report Outcomes Measurement Information System (PROMIS) into Clinical Care in Rheumatic Diseases

Updated 8/23/2012

Purpose of Study: This research is being done to test a new questionnaire administered on iPad tablet device.  It is designed to facilitate a more focused physician-patient interaction to provide an accurate assessment of your overall health, ability to function and take part in life activities, and other aspects of living with arthritis (such as sleep, fatigue, emotions, etc.).

Recruiting Patients: 

  • Patients Diagnosed with Rheumatoid arthritis and Psoriatic arthritis
  • Established patients at the Johns Hopkins Arthritis Center
Coordinator/Contact: Trisha Duncan
410-550-3609
Email: tduncan4@jhmi.edu
Principal Investigator: Clifton O. Bingham, M.D.
IRB#: NA_00071923

Research Database for Spondyloarthritis Patients

Updated 8/22/2012

Purpose of Study:  This research is being done to better understand several important features of “spondyloarthritis”.  Our goal is to develop a database with clinical information, blood samples and joint fluid from people with spondyloarthritis to help better understand the condition.

Recruiting Patients:

  • Diagnosed with ankylosing spondylitis, psoriatic arthritis, reactive arthritis, inflammatory bowel disease-associated arthritis and undifferentiated arthritis.
  • Patients of the Johns Hopkins Arthritis Center.
Coordinator/Contact: Michelle Jones
Phone: 410-550-9674
Email: mrkjones@jhmi.edu
Principal Investigator: Grant H. Louie, MD, MHS
IRB#: NA_00066578

The CORRONA Effectiveness Registry to Study Therapies for Arthritis and Inflammatory Conditions (CORRONA CERTAIN) Sub-study

Updated 8/23/2012

Purpose of Study:  This research is being done to find the effectiveness and safety of certain biologic medications used in the management of rheumatoid arthritis (RA). Biologic therapies (including medications like Enbrel, Humira, Remicade, Cimzia, Simponi, Actemra, Rituxan and Orencia) have changed the treatment of RA. The differences in safety and/or effectiveness of each biologic medication are not all known. We are doing this study in order to try to see if one or more of these treatments are better than the others.

Recruiting Patients:

  • Diagnosed with Rheumatoid Arthritis
  • Patients of the Johns Hopkins Arthritis Center
Coordinator/Contact: Michelle Jones
Phone: 410-550-9674
Email: mrkjones@jhmi.edu
Principal Investigator: Clifton O. Bingham, M.D.
IRB#: NA_00027956

Ongoing Research

Comprehensive Oral Health Assessment in Patients with Arthritis and Autoimmune Inflammatory Diseases

Updated 7/13/2012

Purpose of Study:  The purpose of this research study is to determine whether Periodontal Disease (Gum Disease) is more common or severe in patients with Rheumatoid Arthritis and other Auto immune conditions.

Updated: March 11, 2014

Arthritis Center

About Arthritis Center

Founded in 1998, the Arthritis Center at Johns Hopkins is dedicated to providing quality education to patients and healthcare providers alike.