Home > Arthritis News > 2006 Is There an Increased Risk of Malignancy and Serious Infection Among RA patients Receiving High-dose Anti-TNF Therapy? Whether TNF inhibitor therapy can be independently linked to an increased risk of malignancy or serious non-opportunistic infection has been difficult to discern since RA itself is associated with an increased risk […]
Is There an Increased Risk of Malignancy and Serious Infection Among RA patients Receiving High-dose Anti-TNF Therapy?
Home > Arthritis News > 2006 Effect of Muscle-Derived Stem Cells on Cartilage Repair Articular cartilage possesses little ability for healing, leading to progressive destruction and eventually osteoarthritis in the setting of sustained injury. Current methods to repair damaged articular cartilage, including transplants of cartilage and bone, have had limited success due to a lack […]
Interaction of environment, genetics and autoimmunity in the pathogenesis of rheumatoid arthritis (RA)
Home > Arthritis News > 2006 Interaction of environment, genetics and autoimmunity in the pathogenesis of rheumatoid arthritis (RA) Cigarette smoking and a genetic marker, the HLA-DR shared epitope, have been consistently identified as risk factors for the development of RA (see 2004 news summary). In recent years, the presence of antibodies against citrullinated peptides […]
Home > Arthritis News > 2006 Rituximab Receives FDA Approval for Treatment of Rheumatoid Arthritis The Food and Drug Administration (FDA) has now approved rituximab (Rituxan®) in combination with methotrexate for the treatment of rheumatoid arthritis (RA) in patients with moderate to severe rheumatoid arthritis who have had an inadequate response to one or more […]
Home > Arthritis News > 2006 Sleep Disturbance is Increased in Rheumatoid Arthritis Sleep quality has a profound affect on pain perception and mood, and poor sleep itself may affect immune function by increasing allostatic load. All of these effects may relate to the RA disease process. However, little investigation into sleep disturbance has been […]