Effectiveness of Combination Therapy vs. Monotherapy with Etanercept or Infliximab in Real-World Clinical Practice

Home > Arthritis News > 2006 Effectiveness of Combination Therapy vs. Monotherapy with Etanercept or Infliximab in Real-World Clinical Practice Efficacy studies of TNF inhibitors in rheumatoid arthritis (RA), such as TEMPO, have shown that initial therapy with a TNF inhibitor + methotrexate combination is superior to either drug used as monotherapy. However, in clinical […]

Is There an Increased Risk of Malignancy and Serious Infection Among RA patients Receiving High-dose Anti-TNF Therapy?

Home > Arthritis News > 2006 Is There an Increased Risk of Malignancy and Serious Infection Among RA patients Receiving High-dose Anti-TNF Therapy? Whether TNF inhibitor therapy can be independently linked to an increased risk of malignancy or serious non-opportunistic infection has been difficult to discern since RA itself is associated with an increased risk […]

Effect of Muscle-Derived Stem Cells on Cartilage Repair

Home > Arthritis News > 2006 Effect of Muscle-Derived Stem Cells on Cartilage Repair Articular cartilage possesses little ability for healing, leading to progressive destruction and eventually osteoarthritis in the setting of sustained injury. Current methods to repair damaged articular cartilage, including transplants of cartilage and bone, have had limited success due to a lack […]

Interaction of environment, genetics and autoimmunity in the pathogenesis of rheumatoid arthritis (RA)

Home > Arthritis News > 2006 Interaction of environment, genetics and autoimmunity in the pathogenesis of rheumatoid arthritis (RA) Cigarette smoking and a genetic marker, the HLA-DR shared epitope, have been consistently identified as risk factors for the development of RA (see 2004 news summary). In recent years, the presence of antibodies against citrullinated peptides […]