Does trauma cause rheumatoid arthritis?

I am seriously concerned that i trigerred the onset of RA by doing serious injury to my wrists 3 years ago, suffering blows to both wrists , inside and outside, for no other reason than pure frustration and blunt force trauma. It was totally unecessary and i feel shattered by this. I feel i have left myself and my family down in a moment of madness. My life is ruined over this! I am devastated ! ger

Knee replacement and ankylosing spondylitis

As I have AS since I was 16 years old and I am 61 now I have the most problem with my knee.I was diagnosed to have osteoarthritis. I can’t hardly walk anymore and I am thinking of getting a knee replacement I am anxious that if I would get a knee replacement, if that would fix my problem or would the tissue and bones around the artificial knee still be affected with inflammations and is such an operation useless for me because I have AS. My knee now gets stiff and makes saw like noises. The quality of my life is diminished and I am depressed about it. Can you help me with an answer?

Phosphocitrate

greetings, im a physician and newly diagnosed spondyloarthropic. ive seen several researchers point toward phopshpocitrate as a potent inhibitor of tgf-beta in murine models of AS (j cliford, h krug). infact, its use appears to inhibit or stop ankylosis altogether. i believe bisphosphonates failed to have a similar effect in mice. despite clinical improvement in humans, i know its unclear what effect bisphosphonates have with regard to ankylosis. my question is: are there plans to test phopshpcitrate, or prehaps closer cousins to it, in humans? enjoy, josh

What bed would be best for Ankylosing Spondylitis patients?

My husband has AS and we have been trying to decide what kind of bed would be most ideal for him. We’ve heard mixed reviews about the Tempur-pedic and good reviewes about the Sleep Number beds, but they are incredibly expensive. Are these kinds of beds really best for AS or is there something we should look for that is ideal for his condition? Thank you.

Migratory Reactive Tendonitis?

I am waiting to see a Rheumatologist, as appointments in my area are booked up over two months in advance. For 2 months, in the evening I have acute tendon pain (unilateral, each night somewhere different.) Wrist, thumb, knee, foot, shoulder, elbow. By morning it is always gone. All of my bloodwork came back normal–no to Lyme’s, 3 negative RA tests, no gout, no increased sed rate or sign of infection. My colon feels distended, and I have gained 10 pounds in the last month, which is very, very unusual for me. NSAID’s Mobic is not helping (21 days), now my family doctor wants to prescribe Celebrex.