…with anakinra in combination with DMARDS other than TNF inhibitors, compared to placebo with DMARDs (2 % vs 1%). Opportunistic infections including tuberculosis are less common with anakinra than with…
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Effectiveness of Combination Therapy vs. Monotherapy with Etanercept or Infliximab in Real-World Clinical Practice
…combination therapy with a non-methotrexate DMARD. Of the infliximab treated patients, 9% received monotherapy, 83% combination therapy with methotrexate, and 8% combination therapy with a non-methotrexate DMARD. The most common…
Inhibition of Interleukin-1 as a Strategy for the Treatment of Rheumatoid Arthritis
…total score was observed in the combined IL-1ra groups, compared to placebo, by the Genant scoring method.24, 25 The treatment effect for the combined IL-1ra groups was a 38% reduction…
Managing Chronic Pain and Depression in Arthritis
…HMO members, the prevalence of depression was 12% in individuals with 3 or more pain complaints compared to only 1% in those with one or no pain complaints (Dworkin et…
Rehabilitation of Older Adult Patients with Arthritis
…Nonpharmacologic options foot pumps intermittent pneumatic compression graded compression elastic stockings Surgery Best Also good Total knee arthroplasty Low Molecular Weight Heparin Intermittent Pneumatic Compression with Low Molecular Weight Heparin…
Osteoporosis Update
…women aged 80 years or older. However, compared with nonusers, current estrogen users had a 33% lower age-adjusted mean rate of loss at the total hip. There are no completed…